Document Type : Original Article
Author
Tikrit University / College of Food Sciences, Al-Sharqat
Abstract
Abstract:
Using a cross-sectional methodology, blood samples were subjected to ELISA analysis to quantify rubella IgM, rubella IgG, and anti-dsDNA antibody concentrations in order to ascertain the correlation between rubella immunological indicators, specifically IgM and IgG, and anti-dsDNA antibody concentrations in a sample of fifty-nine reproductive-age women; Rubella IgM levels were consistently low throughout the study group, indicating the absence of acute infection, while rubella IgG levels showed significant variability, likely reflecting differences in prior exposure or immunity. Anti-dsDNA antibody levels were highly variable; some showed markedly elevated concentrations, indicating subclinical autoimmune activity; a noteworthy finding was the progressive increase in anti-dsDNA levels among women who had two or three abortions, a group that also showed the most prominent outlier titers, strongly indicating the involvement of autoimmune processes in recurrent pregnancy loss within a particular subset of women; participants who had six or more abortions showed normal dsDNA levels, indicating that extreme recurrent pregnancy loss is likely due to non-autoimmune causes, Rubella IgM levels did not correlate with anti-dsDNA.
Keywords
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